Xeomin® in Toronto & Markham: Pure Neurotoxin
Xeomin® is Merz Aesthetics' botulinum toxin type A, and its defining characteristic is"naked molecule"formulation (free of complexing proteins), which theoretically carries the lowest risk of antibody formation with long-term use.
Quick Answer
Xeomin® (incobotulinumtoxinA) is a prescription neuromodulator made by Merck, authorized in Canada to temporarily reduce moderate-to-severe frown lines and other dynamic wrinkles. It is suitable for adults seeking a clinically tested botulinum toxin option. Xeomin® works by blocking nerve signals to targeted facial muscles, softening movement-related lines. At ID Cosmetic Clinic in Markham and Toronto, Xeomin® injections are performed personally by physician Dr. Dan Xu, M.D., CCFP. Results typically appear within 3–7 days and last approximately 3–4 months; repeat sessions help maintain outcomes.
View Contents (14)
- 01 Dr. Xu's Rea…
- 02 Why Choose ID Cos…
- 03 What is Xeomin® —…
- 04 How Xeomin® Works
- 05 Am I a Candidate …
- 06 Xeomin® Treatment…
- 07 Indications Treat…
- 08 Pre-Procedure Ins…
- 09 Advantages of Xeo…
- 10 Dr. Dan Xu, M.D.,…
- 11 《Timeless Asian B…
- 12 Why Trust ID Cosm…
- 13 Xeomin® Pricing &…
- 14 Common Risks · Co…
Dr. Xu's Real Cases: Xeomin®
Real clients treated personally by Dr. Dan Xu at ID Cosmetic Clinic in Markham. Every client signed a Media Release Form. Photos are unretouched clinical records; results vary between patients with skin type and aftercare, and are not guaranteed.
01Heavy Mature Jowls Lifted
- Treatment
- neuromodulator injections, Belotero®, Chin Filler, Lip Filler Augmentation, Temple filler, Forehead Filler Augmentation, HA Filler (Juvéderm® and others), Teosyal®, Collagen Stimulator (Bellafill®, etc.), Perioral Rejuvenation and Eye Rejuvenation / Brightening Injections combined to lift the jowls and reveal the jawline; on this page the focus is lower-face sagging.
- Maintenance
- Continued sun protection and moisturising; review as scheduled to assess maintenance.
02Mature Corner Lines Lifted In Profile
- Treatment
- Chin Filler, HA Filler (Juvéderm® and others), Restylane®, Stylage®, Teosyal®, Teosyal® Hydrafill Skin Booster, Yvoire®, Collagen Stimulator (Bellafill®, etc.), Perioral Rejuvenation, Eye Rejuvenation / Brightening Injections, neuromodulator injections, masseter reduction with neuromodulator injections and Sofwave™ combined to lift the downturned corner lines.
- Maintenance
- Continued sun protection and moisturising; review as scheduled to assess maintenance.
03Round Face Narrowed, Chin Lengthened
- Treatment
- Masseter reduction with neuromodulator injections combined with Chin Filler to narrow the lower face and lengthen the chin.
- Maintenance
- Review as scheduled and top up if needed to maintain.
04Bulky Calf Muscles Made Slender
- Treatment
- Calf Slimming Injection (neuromodulator injections) as a single treatment to relax and reduce the calf muscles.
- Maintenance
- Review as scheduled and top up if needed to maintain.
05Mature Face Lifted And Refreshed Overall
- Treatment
- PicoSure®, Ultherapy® and neuromodulator injections combined to lift the face and improve tone and wrinkles.
- Maintenance
- Continued sun protection and moisturising; review as per the treatment schedule to maintain.
06Static Forehead Lines Filled
- Treatment
- HArmonyCa™ (HA + Collagen Biostimulator) and Collagen Stimulator (Bellafill®, etc.) combined to fill static forehead lines.
- Maintenance
- Continued sun protection and moisturising; review as scheduled to assess maintenance.
07Mature Forehead Lines Relaxed
- Treatment
- neuromodulator injections as a single treatment to relax the forehead lines.
- Maintenance
- Continued sun protection and moisturising; review as scheduled to assess maintenance.
08Chin Pushed Forward In Three-Quarter View
- Treatment
- HA Filler (Juvéderm® and others) as a single treatment to correct the receding chin.
- Maintenance
- Review as scheduled and top up if needed to maintain.
09Retrusion Corrected In Side View
- Treatment
- Chin Filler combined with HA Filler (Juvéderm® and others) to correct the receding chin.
- Maintenance
- Review as scheduled and top up if needed to maintain.
10Defined Jawline, Refined Face Shape
- Treatment
- Neuromodulator injections combined with Chin Filler to narrow the lower face and define the jawline.
- Maintenance
- Review as scheduled and top up if needed to maintain.
← swipe for more →
Why Choose ID Cosmetic Clinic for Xeomin® in Toronto
Technology defines the possibilities. The physician defines the direction.Xeomin the “bare-molecule” characteristic means the injecting physician requires more precise dosing and placement control — Without the “buffer” of complexing proteins, binding at the nerve terminal is more direct, placing greater demands on injection technique.
Specialist in Asian facial aesthetics
Dr. Xu specializes in Asian facial anatomy and muscle architecture. He has a thorough understanding of the dosing differences Xeomin requires when treating the thinner mimetic muscles common in Asian women, and carefully avoids over-correction pitfalls such as lateral brow ptosis and stiffened smile — concerns particularly relevant to Asian faces.
Merz Canada training certification
Dr. Xu holds official Merz Canada certification in Xeomin injection training — Merz being the global manufacturer of Xeomin. He has an in-depth command of incobotulinumtoxinA’s “naked molecule” 150 kDa structural profile, antibody avoidance strategies, and dosage optimization logic for long-term maintenance patients.
80,000 injection procedures performed
With extensive experience across all major neuromodulator brands — Xeomin®, Botox®, Dysport®, Letybo®, and Nuceiva® — Dr. Xu tailors each treatment to yourantibody risk, allergy history, desired onset, and maintenance duration preferencepersonalized treatment plans, with particular expertise in switching prescriptions for patients experiencing Botox® non-response.
All Four Major Neurotoxin Platforms Available
The clinic carries Xeomin® / Botox / Dysport / Letybo, Switching brands or combining treatments based on your antibody history, allergy profile, and treatment area needs when appropriate dermal fillerfilling static lines.
Bilingual consultations in English and Mandarin
Consultations are conducted in both Mandarin and English, ensuring you fully understand what sets Xeomin® apart from other neuromodulators — its pure-form molecule, how it reduces antibody risk, and why Dr. Xu may recommend it for your specific situation (especially if you are considering switching after long-term use of another brand).
Conveniently serving both Toronto and Markham
Our clinic is conveniently located on the border of Toronto and Markham, serving the Chinese-Canadian community across the Greater Toronto Area (GTA) — including North York, Richmond Hill, Scarborough, and Vaughan. Evening and weekend appointments are available.
- FDA Health Canada–licensed Xeomin® (2010 for aesthetic indications · 2011 for upper limb spasticity) · Health Canada DIN registered
- Merz Canada Official Xeomin® Certified Training Physician
- Allergan / Juvéderm North America Official Trainer (peer-to-peer training)
- CPSO Registered and licensed physician in Ontario (publicly verifiable with CPSO)
- All neuromodulator injections are performed personally by Dr. Dan Xu, M.D. — never delegated to a technician
- Google 4.9★ · 283 Authentic patient reviews
What is Xeomin® — the pure neuromodulator?
Xeomin® (is a product of Merz Pharmaceuticals, Germany, A botulinum toxin type A (incobotulinumtoxinA)formulation, Health Canada–licensed in 2010 for the aesthetic treatment of glabellar lines, and isThe world’s third-largest neuromodulator brand. Its core differentiator isProprietary XTRACT Technology™ purification process — removing all complexing proteins (accessory proteins), retaining only the active 150 kDa Neurotoxin molecule, also known as the “naked molecule.”
Botox and Dysport®, the toxin molecule is bound to 900 kDa Complexing proteins (hemagglutinins + non-hemagglutinin proteins) — these complexing proteins contribute nothing to treatment efficacyno direct contribution, howeverthe primary antigenic source recognized by the immune system. After repeated long-term injections, some patients develop antibodies targeting the complexing proteinsneutralizing antibodies, leading to diminished Botox® efficacy or complete loss of response (treatment failure / Secondary Treatment Failure).
Xeomin By removing complexing proteins, the formulation theoretically reducesantibody formation riskreduced to a minimum — which is why Dr. Xu designates Xeomin® aslong-term maintenance patients, Botox® non-responders, and patients with milk protein allergiesthe preferred formulation. In terms of dosing, Xeomin® and Botox® are approximately 1:1 Conversion (far more intuitive than Dysport®’s 1:2.5 conversion), with onset in 5–7 days and duration of 3–4 months, comparable to Botox®.
Device / Formulation Technical Specifications
- Generic nameincobotulinumtoxinA
- molecular structure150 kDa””Bare molecule” · Free of complexing proteins
- mechanism of actionBlocks SNAP-25 protein · Inhibits acetylcholine release
- Onset time5-7 days (comparable to Botox®)
- duration3-4 months
- Health Canada–licensed2010 Medical Aesthetics · Health Canada–licensed
- ManufacturerMerz Pharmaceuticals (Germany)
Xeomin Comparison with other neuromodulators
| Brand | molecular structure | Antibody risk | Dose conversion |
|---|---|---|---|
| Xeomin® | 150 kDa naked molecule | Minimum | 1:1 vs Botox |
| Botox® | 900 kDa Complexing proteins | Moderate | baseline |
| Dysport® | 500-900 kDa combination | Moderate | 1:2.5 vs Botox |
| Letybo® | 900 kDa Complexing proteins | Moderate–Low (Newer Generation) | 1:1 vs Botox |
Note: Xeomin® is currently the only commercially available “protein-free” botulinum toxin type A. Switching to Xeomin® can significantly lower the risk of neutralizing antibodies in patients on long-term maintenance treatment.
How Xeomin® Works
Xeomin shares the sameMolecular mechanism (blocking SNAP-25 protein) — however, due to its “naked molecule” structural difference, its immunological behavior is subtly distinct. Dr. Xu will customize injection points and dosage based on your muscle strength and target areas.
Consultation and antibody history assessment
Dr. Xu assesses your muscle activity by asking you to perform facial expressions (raising eyebrows / frowning / smiling / pursing lips) to evaluate yourDynamic muscle strength, with a focused review of your neuromodulator history: Has your maintenance period shortened? Have you noticed diminishing onset effects? These clues determine whether Xeomin® should be the preferred choice.
Customized dosing (1:1 conversion)
Xeomin Unit dosing comparable to Botox® 1:1 Conversion ((e.g., Botox 20U for glabellar lines → Xeomin 20U) — the dose conversion is more straightforward than with Dysport. Dr. Xu determines your dosage based on muscle strength and facial symmetry, taking a conservative approach on the first treatment.
Precision point-placement injection
Ultra-fine 30–32G needles are used for multi-point, superficial injections along the muscle fibers. Xeomin®’s “naked molecule” has moderate diffusion — between that of Botox® and Dysport®. The entire procedure takes 5–10 minutes, with minimal discomfort (comparable to a mosquito bite).
5-7 days to onset
Xeomin Onset is similar to Botox® (approximately 2–3 days slower than Dysport®). Patients typically notice muscle heaviness by days 5–7, with full effect achieved by days 10–14.Do not self-administer additional units if results seem absent in the first week — allowing the bare-molecule neurotoxin sufficient time to bind to nerve terminals.
3-4 month maintenance period
Results from the first injection typically last 3–4 months, comparable to Botox®.Key advantage for long-term use: After 5–10 years of continuous use, Xeomin®’s maintenance period does not shorten due to antibody formation the way Botox® can — this is the core clinical value of its “naked molecule” structure.
Antibody Risk Management — Dr. Xu’s Three-Layer Defense
Neutralizing antibodies are one of the most underrecognized complications in long-term neuromodulator patients. Dr. Xu employs a three-layer strategy to minimize the risk of antibody formation.
“Bare-molecule” formulation — preferred choice
For patients with 5+ years of continuous neuromodulator use or those experiencing reduced efficacy from Botox®, Dr. Xu often recommends Xeomin® as the preferred option — removing the complexing proteins eliminates the primary antigenic source.
12 Week interval guideline
Regardless of which neurotoxin is used, Dr. Xu maintains a strict minimum interval of 12 weeks between injections to prevent overly frequent immune system exposure and antibody formation.
Minimum effective dose
We never aim for a frozen face. Treatment begins at the lowest effective dose (glabellar lines 18–22 U) to minimize cumulative antigen exposure over time.
In my 80,000 injection experience, at least 30–50 patients per year come to me with diminished Botox® response — approximately 60% of them fully regain their maintenance period after switching to Xeomin®. This is not a case of “Botox® failure”; it is the immune system recognizing the complexing proteins.Xeomin Its true value is not about “replacing Botox®” — it’s about “preserving Botox® as a future option.” — Dr. Dan Xu, M.D., CCFP · Merz Certified Xeomin Injector
Am I a Candidate for Xeomin® (incobotulinumtoxinA)?
You are welcome to do a self-assessment before your consultation, but whether you are a suitable candidate must be determined by Dr. Xu throughdynamic muscle assessment + prior neurotoxin history review + allergy screening— making it particularly the right answer for patients experiencing diminishing Botox® results or those with a milk-protein allergy.
You may be a candidate for treatment if…
- prior diminishing effect or shortened duration with Botox® or Dysport®
- planLong-term repeated injections (5 years or more of aesthetic maintenance)
- Severe milk-protein allergy (contraindication for Dysport®)
- Dynamic lines (glabellar lines / forehead lines / crow’s feet)
- Patients who prioritize natural expression retention (actors, on-camera hosts, teachers)
- Concerns about or immune sensitivity to complexing protein components
- Patients seeking the “purest” available formulation
- Patients with allergy-prone skin should prioritize formulations with a simpler excipient profile.
Treatment is not recommended if any of the following apply…
- Pregnancy or breastfeeding
- Neuromuscular disorders (myasthenia gravis, Lambert-Eaton syndrome, ALS)
- Active infection or inflammation at the injection site
- Allergy to incobotulinumtoxinA or human serum albumin
- Currently taking aminoglycoside antibiotics
- received another neurotoxin brand within the past 3 months
- For large-area treatment requiring faster onset, Dysport® is recommended.
- Unrealistic expectations, or those seeking a completely frozen face (not recommended for Asian faces)
Clinical Scenario vs. Neuromodulator Brand — Dr. Xu’s Recommendation Guide
In different clinical scenarios, Dr. Xu has clear brand preferences — Xeomin® is the first choice for long-term maintenance and patients with antibody risk sensitivity:
| clinical scenario | First choice | Secondary option | Reason |
|---|---|---|---|
| Long-Term Maintenance (5+ Years) | Xeomin | Letybo | Lowest antibody risk profile |
| Botox Reduced efficacy over time | Xeomin | Dysport | “”Bare molecule” — minimizes antibody formation |
| milk protein allergy | Xeomin | Botox | milk protein-free |
| first-time injection patients | Botox | Xeomin | Strongest clinical evidence base |
| Fast onset ideal for pre-wedding preparation | Dysport | Botox | 2-5 days to onset |
| broad-coverage forehead line treatment | Dysport | Xeomin | DCR Diffusion profile |
| Corner of mouth / upper lip refinement | Botox / Letybo | Xeomin | precise control |
Xeomin® Treatment Planning
Xeomin Neuromodulator injection is a physician-customized treatment. What Dr. Xu designs is3-4 Monthly periodic maintenance plan. For long-term patients, it is recommended toRegular intervals of 12 weeks or more, minimizing the risk of antibody formation.
Initial Consultation & Antibody History Assessment
Free 30-Minute Consultation, including dynamic expression assessment + review of prior neurotoxin history + allergy screening + explanation of the “naked molecule” mechanism.
Customized dosing (1:1 conversion)
Dr. Xu converts Xeomin® doses at a 1:1 ratio based on the patient’s previous Botox® units (glabellar lines 20U / bilateral crow’s feet 20U / forehead lines 12–16U), starting conservatively at the first session.
D14 follow-up touch-up
D14 is the assessment window for Xeomin®’s full effect. Dr. Xu evaluates symmetry and coverage, with a 5–10U touch-up if needed (complimentary at the first treatment).
3-4 monthly cycle maintenance
We recommend scheduling your next session when you notice about 70% of the effect has worn off — rather than waiting until it has fully faded. With long-term Xeomin® use, treatment intervals remain stable and are not shortened by antibody development.
Typical Treatment Cycle Timeline
Below is the standard timeline for Xeomin® clients, from initial consultation through the maintenance phase:
| Timeline | Content |
|---|---|
| Day 0 | Free 30-Minute Consultation (dynamic muscle assessment + neurotoxin history review + antibody risk discussion) |
| Day 0 (Injection) | Injection can be performed immediately after consultation · Entire procedure takes 5–10 minutes |
| D5-D7 | Initial onset · Muscles begin to feel heavier |
| D10-D14 | Full effect achieved · Dynamic lines visibly reduced |
| D14 Follow-up | Symmetry and coverage assessment · Touch-up of 5–10 U if needed (complimentary at first follow-up) |
| Months 3–4 | 50–70% of effect has worn off · Entering the maintenance injection window |
| 3 times per year | Regular intervals of 12 weeks or more · Stable long-term maintenance |
The specific units and treatment cycle are customized by Dr. Xu at consultation, based on your muscle strength, target areas, and antibody history.
Indications Treatable with Xeomin®
Xeomin With consistent results in dynamic wrinkle treatment and delicate areas, Dr. Xu has developed dosing protocols equivalent to Botox® (1:1 conversion) specifically for glabellar lines, forehead lines, crow’s feet, and fine-detail adjustments commonly seen in Asian faces.
Glabellar lines (“11” lines)
Dynamic contraction of the corrugator supercilii and procerus muscles; 20U of Xeomin® is the Health Canada–licensed dose for this indication — equivalent to Botox®.Dynamic linesOver 80% improvement with standardized 5-point injection technique.
20U / Every 3–4 monthsForehead Lines
For dynamic horizontal forehead lines caused by the frontalis muscle, Xeomin® 12–20 U performs excellently on average-sized foreheads. Its “bare-molecule” formulation offers moderate diffusion, making it well suited for standard-coverage forehead treatment — not ideal for unusually large surface areas.
12-20U / Every 3–4 monthsCrow’s feet
For dynamic lateral contraction of the orbicularis oculi, Xeomin® 8–12 U per side allows precise control of diffusion,preserving the natural eye-corner creases when smiling — The preferred choice for actors and on-camera professionals.
16–24 U bilateral / every 3–4 monthsBotox Resistance-based switching
For patients who have received Botox® continuously for five or more years and are noticing a shorter duration of effect, Dr. Xu recommends a 3-month Botox® washout before switching to Xeomin® — 60% of such patients regain their full maintenance period, confirming the suspected antibody effect.
1:1 unit conversion from prior Botox® dosageBrow Lift
Selectively relaxing the brow depressor muscles produces a subtle brow lift. With a precise micro-dose of Xeomin® 4–10 U, we avoid the over-arched “surprised” look, delivering the soft, natural brow elevation that Asian women tend to prefer.
4-10U / Every 3–4 monthsMasseter hypertrophy / facial slimming
A popular treatment among Asian women. For masseter hypertrophy, Xeomin® 30–50 U per side effectively reduces muscle volume. Its low antibody risk makes it especially suitable for patients who require repeated long-term treatment.
60–100 U bilateral / every 4–6 monthsGummy Smile
Overactive levator labii superioris alaeque nasi (LLSAN) muscles can cause excessive gum show when smiling. A precise Xeomin injection of 2–4 U per side into the LLSAN restores a natural smile arc, while the “naked molecule” formulation’s controlled diffusion minimizes any impact on lip shape.
4-8U / Every 3–4 monthsNeck Rejuvenation (Nefertiti Lift)
For platysmal banding, Xeomin injected along the bands at 40–60 U can soften their appearance and provide a subtle jawline lift. For patients undergoing repeated neck rejuvenation treatments, Xeomin carries the lowest antibody risk of any available neuromodulator.
40-80U / Every 3–4 months8 Core Indications × Xeomin® Dosage × Treatment Cycle Reference Table
| Indications | Xeomin dosage | ≈ Botox units | Maintenance interval |
|---|---|---|---|
| glabellar lines | 20U (FDA) | 20U | 3-4 months |
| forehead lines | 12-20U | 12-20U | 3-4 months |
| Crow’s feet | 16–24 U bilateral | 16–24 U bilateral | 3-4 months |
| brow lift | 4-10U | 4-10U | 3-4 months |
| Masseter slimming | 60–100 U bilateral | 60–100 U bilateral | 4-6 months |
| Gummy smile | 4-8U | 4-8U | 3 months |
| Neck Lines — Nefertiti Lift | 40-80U | 40-80U | 3-4 months |
| Botox Switch | Based on prior 1:1 dosing | Original dosage | same as prior |
Pre-Procedure Instructions · Injection Process · Post-Care
There is minimal downtime after Xeomin® treatment, but the care you take in the first 4 hours post-injection can influence the final symmetry and longevity of results. Dr. Xu reviews each aftercare step with you before you leave.
pre-procedure preparation
- Avoid aspirin, ibuprofen, and Omega-3 supplements for 1 week before injection (to minimize bruising). Do not stop a prescribed medication without your prescriber’s advice.
- Avoid alcohol (for 24 hours prior to injection)
- Disclose all current medications (including antibiotics and antihypertensives)
- Arrive without makeup on the injection area. Eating normally beforehand is fine.
- A complete neurotoxin history is required — including brand, dosage, and any history of diminishing or shortened effect.
- Please inform us of any human serum albumin allergy (one of Xeomin®’s only excipients).
During the injection
- Cleanse the face + mark muscle injection points (3–5 minutes)
- Administered via 30–32G fine needles using a multi-point superficial injection technique
- A mild, mosquito-bite-like sting — usually well tolerated
- Single injection session: 5–10 minutes (depending on number of areas treated)
- Small red dots or minor swelling at injection sites may appear immediately after treatment (typically resolving within 30 minutes).
Post-procedure care
- Remain upright for 4 hours following injection (do not lie flat, to help prevent toxin diffusion)
- Avoid massaging, rubbing or pressing the injection area for 24 hours after treatment unless Dr. Xu instructs you otherwise.
- For 24 hours after treatment, avoid hot yoga, saunas, and intense exercise.
- Avoid alcohol for 24 hours after treatment (increases bruising risk)
- Return to work and social activities immediately after injection (minimal downtime)
- D14 Follow-up assessment of symmetry and coverage (complimentary touch-up on first treatment)
- Daily SPF 50+ sun protection (not directly related to neuromodulators, but important for overall skin health). Tell us if you plan to fly soon after treatment.
D0-D30 Full onset timeline
| Duration | What Clients Should and Should Not Do |
|---|---|
| D0 (on the day of injection) | Remain upright for at least 4 hours · No massage · Do not lie down · Ask us before applying makeup over small injection marks |
| D1-D4 | Possible mild sensation of tightness · Occasional bruising · No disruption to daily activities |
| D5-D7 (initial results visible) | Muscles begin to feel heavier · Dynamic lines start to soften · Do not self-administer additional injections simply because full effect has not yet appeared. |
| D10-D14 (full effect achieved) | Dynamic lines visibly reduced · Often noticeable in photo comparison |
| D14 (follow-up window) | Symmetry assessment · small touch-up if needed (complimentary at first follow-up) |
| D30+ | Stable phase · Entering a 3–4 month maintenance cycle |
Advantages of Xeomin®
Technology defines what is possible; the physician defines the direction. Xeomin’s “naked molecule” pure formulation, combined with its lowest antibody risk profile and straightforward 1:1 Botox conversion, gives physicians a safer option for long-term maintenance patients.
“bare-molecule 150 kDa
The only neuromodulator formulated without complexing proteins — a pure preparation.
Lowest antibody risk profile
Long-term repeated injections are unlikely to generate neutralizing antibodies.
1:1 Botox Conversion
Dosing is straightforward, without the 1:2.5 conversion complexity of Dysport®.
milk protein-free
Excipients consist only of human serum albumin and sucrose — formulated to be well-tolerated by those with sensitivities.
3-4 months of stable maintenance
Comparable to Botox® · Long-term use does not shorten the maintenance period.
FDA & Health Canada–licensed
FDA 2010 Approved aesthetic indications · Third-largest neurotoxin brand worldwide.
Minimal downtime
You can return to work and social activities immediately after injection with no significant downtime.
Preferred Choice for Performers & Streamers
Fine-tuned control that preserves natural expression — results that never look “done.”
Xeomin vs Botox vs Dysport vs Letybo Four Neurotoxin Brands Compared
| Brand | molecular structure | Onset time | Antibody risk | Unit Price (CAD/U) |
|---|---|---|---|---|
| Xeomin® | 150 kDa naked molecule | 5-7 days | Minimum | Consultation-based pricing |
| Botox® | 900 kDa Complexing proteins | 3-7 days | Moderate | Consultation-based pricing |
| Dysport® | 500-900 kDa combination | 2-5 days | Moderate | Consultation-based pricing (×2.5) |
| Letybo® | 900 kDa Complexing proteins | 3-5 days | Moderate–Low (Newer Generation) | Consultation-based pricing |
Note: Xeomin® is currently the only commercially available “protein-free” botulinum toxin type A. Switching to Xeomin® can significantly reduce the risk of neutralizing antibodies in long-term treatment patients. For brand selection guidance, refer to our Neurotoxin Brand Comparison Guide.
Dr. Dan Xu, M.D., CCFP
ID Cosmetic Clinic Founder & Medical Director · Author of Timeless Asian Beauty · Merz Certified Xeomin Injector
As a highly respected Chinese-Canadian medical aesthetic expert in Toronto, Dr. Dan Xu is recognized for herexceptional clinical expertise, a refined aesthetic sensibility, and a deep cultural understandingand is known for her work with over 80,000 proceduresinjection and laser clinical experience, encompassing refined use of leading neurotoxin brands including Xeomin®, Botox®, Dysport®, and Letybo®.
Dr. Xu holds Merz Xeomin® Canada Training Certification (Merz is the global manufacturer of Xeomin), with a thorough command of incobotulinumtoxinA’s “naked molecule” 150 kDa structural properties, antibody-avoidance strategies, and dose optimization for long-term maintenance patients. She manages 30–50 patients per year who experience diminished Botox® response, achieving approximately 60% successful outcomes after switching to Xeomin®.
Her aesthetic philosophy is both concise and profound:“Beauty should help you become a better version of yourself — not change who you already are.” — This means Xeomin® injections at our clinic are never prescribed to create a “frozen face” — preserving natural expression movement is a priority for Asian faces.
Professional Certifications & Credentials
- Education — M.D. + Family Medicine Specialty (CCFP)
- Authority — Merz Canada Xeomin® Certified Training Physician
- Authority — Allergan / Juvéderm North America Official Trainer
- Authority — Galderma Dysport® Canada Training Certification
- Authority — Candela Medical Canada KOL
- Authority — Cynosure PicoSure Pro Canada KOL
- Authority — Sofwave Key Opinion Leader
- Authority — McMaster University Clinical Preceptor (clinical teaching physician)
- Authority — IMCAS International aesthetic medicine conference speaker
- Trust — CPSO Registered physician · Publicly verifiable
- Trust — Author of Timeless Asian Beauty (2024)
《Timeless Asian Beauty》
Timeless Asian Beauty, authored by Dr. Dan Xu, is a book written specifically forAsian facesA landmark guide to aesthetic self-discovery — crafted with care and precision. Rather than imposing rigid beauty standards, this book invites readers to explore beauty through the lens of culture, anatomy, and self-awareness.redefining beauty. The book’s coverage ofAntibody Management Strategy for Long-Term Neuromodulator Patients, serves as the clinical blueprint for Xeomin® prescribing at ID Cosmetic Clinic.
Drawing on his cross-border clinical experience across China, Korea, and Canada, Dr. Xu challenges the long-dominant Western-centric aesthetic bias in the book — for the first time addressingThe skeletal structure, mimetic muscle orientation, and aging patterns of Asian faces, has proposed a systematic long-term neurotoxin maintenance framework — encompassing a complete strategy for brand switching, dose titration, and antibody avoidance.
This book focuses on the essence of Asian aesthetics —Natural, soft, and expressive. Dr. Xu emphasizes in his book: a well-designed neuromodulator treatment is never about a “frozen face” — it is aboutSoftens dynamic lines while preserving natural expression movement — This aligns perfectly with the precision-injection philosophy behind Xeomin®’s “bare-molecule” formulation.
Identify with your own beauty.
Identify with your own beauty. — Dr. Dan Xu, M.D.
Why Trust ID Cosmetic Clinic for Xeomin® Treatments?
Real-world injection experience
- 10+ years of dedicated clinical practice in neuromodulator injections
- 80,000 cumulative injection procedures performed
- Has treated hundreds of patients switching to Xeomin® due to reduced Botox® efficacy
- Complete Before & After photo records for every patient
Medical professional training
- M.D. Full medical school training and education
- CCFP Family medicine specialty certification (CCFP)
- specialized knowledge of facial anatomy and neuromuscular mechanisms
- 150 kDa”In-depth understanding of the bare-molecule structure and its immunological implications
- 4 Expert in cross-brand neuromodulator dose conversion
industry-recognized credentials
- Merz Canada Xeomin® Certified Training Physician
- Allergan / Juvéderm North America Official Trainer
- Galderma Dysport® Canada Training Certification
- Candela Medical Canada KOL
- Cynosure PicoSure Pro Canada KOL
- Sofwave Key Opinion Leader
- McMaster University Clinical training physician
- IMCAS International conference speaker
Transparent and verifiable
- CPSO Registered practicing physician (publicly verifiable)
- Google 4.9★ · 283 Authentic patient reviews
- Written informed consent form signed + unit documentation recorded at every injection session
- All Before & After photos are unretouched
- Author of Timeless Asian Beauty (2024)
Xeomin® not a “synonym for Botox®,” but rather “a purer choice designed for long-term patients”
Xeomin Both Botox® and Xeomin® are botulinum toxin type A products; however, Xeomin® uses the proprietary XTRACT Technology™ to remove the complexing proteins, retaining only the 150 kDa neurotoxin core — which meansThe antigenic source responsible for long-term immune exposure is eliminated. For patients who have been receiving Botox® or Dysport® for more than five years, Xeomin® is the most reliable option for preventing treatment resistance.
As a Merz-certified injector, Dr. Xu does not recommend Xeomin® to every patient — instead, recommendations are based on yourinjection history, antibody risk, allergy history, and desired onsetPersonalized decision-making. The true value of Xeomin® is not simply “replacing Botox®” — it ispreserving Botox® as a viable option for future use.
Xeomin® Pricing & Payment
Pricing based onUnitPer-unit pricing for Xeomin® is comparable to Botox® (typically $1–2 CAD less per unit).Following your Free 30-Minute Consultation, Dr. Xu will personalize the unit dosage and provide a tailored quote.Note: Xeomin® uses a 1:1 conversion with Botox® — your existing Botox® dosage transfers directly.
Priced per unit · Glabellar lines 20 U / Forehead lines 12–20 U / Crow’s feet (bilateral) 16–24 U
Botox Switch to Xeomin® · 1:1 conversion from prior dosage · Annual maintenance packages available at a discount
- We accept VISA / Mastercard / Amex / Debit / E-transfer
- Affirm / PayBright financing available (select treatment packages)
- Private Insurance: Some extended health benefit (EHB) plans may cover consultation fees — please inquire for your specific case
- OHIP:Cosmetic procedures are not covered by insurance.
- All new patients receive a 30-minuteComplimentaryConsultation & Assessment
Common Risks · Contraindications · Safety Protocols
We openly share all possible reactions, serious risks, contraindicated populations, and absolute exclusions — so you arrive at your consultation fully informed. Before every injection, Dr. Xu will walk you through Xeomin’s risk profile and antibody management strategy, point by point.
Common reactions (may occur in the short term following injection)
- Mild redness and swelling / small raised bumps at injection sites (30 minutes to 2 hours to resolve)
- Bruising (5-7 days to resolve naturally; Arnica may be used to accelerate recovery)
- Sensation of tightness or heaviness in the head (D1-D5 common, typically subsides with time)
- Mild headache (24-48 hours; acetaminophen may be taken for relief)
- soreness or pressure at injection sites (Mild weakness in chewing for 1–2 weeks after masseter injections is normal.)
Serious Risks (rare, but important to disclose)
- Ptosis (upper eyelid droop)— Most commonly associated with diffusion to the levator palpebrae muscle during glabellar injections. Dr. Xu’s precise injection placement keeps this risk below 1%. If it occurs, it typically resolves on its own within 4–6 weeks; Apraclonidine eye drops may be used to speed recovery.
- Lateral brow ptosis / facial asymmetry— Xeomin Moderate diffusion may occasionally be noticeable in Asian women with thinner mimetic muscles. A day-14 follow-up allows a 5–10 U touch-up to refine symmetry if needed.
- Unnatural smile— diffusion into the zygomaticus major during crow’s feet injections; Dr. Xu avoids this by maintaining a distance of 1.5 cm+ from the lateral canthus
- allergic reaction— Extremely rare (Xeomin®’s excipients contain only human serum albumin and sucrose); patients with known allergies should inform their provider.
- Antibody formation (treatment failure)— Xeomin Antibody risk is already the lowest among the four major brands, but long-term high-frequency injections still require a minimum 12-week interval to reduce risk.
- Infection at the injection site— Extremely rare; preventable with proper sterile technique.
Absolute contraindications (treatment not performed)
- Pregnancy / Breastfeeding
- Neuromuscular disorders (myasthenia gravis, Lambert-Eaton syndrome, ALS, multiple sclerosis)
- Active infection or inflammation at the injection site
- Severe allergy to incobotulinumtoxinA or human serum albumin
- Currently taking aminoglycoside antibiotics (e.g., gentamicin, which may potentiate toxin effects)
- Received another neuromodulator brand within the past 3 months (to avoid compounding antibody risk)
- Unrealistic expectations (demanding a completely frozen face or perfect symmetry)
- periods of depression, anxiety, or emotional instability (stabilizing mental health is recommended first)
Safety Protocols Enforced by Dr. Xu
- Every patient undergoes a dynamic muscle assessment + prior neurotoxin history review + antibody risk discussion before each injection.
- Written informed consent form signed before every injection, with detailed unit documentation
- All injections are scheduled at a minimum of 12 weeks apart (to reduce antibody formation).
- All Xeomin® injections are performed personally by Dr. Dan Xu (M.D.) and are never delegated to a technician
- D14 Mandatory follow-up to assess symmetry · Complimentary touch-up included for first treatment
- Cumulative unit records maintained · Ongoing monitoring for signs of diminishing effect
- Xeomin Product sourced through Merz Canada’s domestic cold chain · Stored at 2–8°C throughout
Your Top Questions About Xeomin®
Xeomin "naked molecule"The formulation is a key clinical consideration for long-term neuromodulator users. The following five questions come up most often during consultations.
Xeomin What is the fundamental difference compared to Botox® and Dysport®?
Dosing is comparable to Botox® (approximately 1:1 conversion). The key difference lies in the formulation: Botox® / Dysport® contain"Complexing proteins"(neurotoxin + complexing proteins), Xeomin® is"naked molecule"(containing only the 150 kDa neurotoxin core, with no accessory proteins. This theoretically reduces the risk of antibody formation with long-term use.
Who Is the Best Candidate for Switching to Xeomin®?
(1) Those who have experienced diminishing results after 2+ years of regular Botox® or Dysport® use (possible antibody development); (2) those with sensitivity to complexing proteins; (3) patients seeking"most purified"ingredient sensitivities; (4) patients with autoimmune conditions in a stable phase (requires physician assessment).
Xeomin Onset and Duration of Effect?
Similar to Botox® — onset in 3–7 days, peak effect at 2 weeks, lasting 3–4 months. For most indications, results are clinically equivalent to Botox®, which is why Xeomin® is often used as"Restarting efficacy by switching brands"the right choice.
Xeomin Which treatment areas are suitable?
All Botox® indications apply: dynamic lines (glabellar lines / forehead lines / crow's feet), masseter slimming, hyperhidrosis, and trapezius (shoulder) injections. Dosing follows Botox® as the reference. In delicate areas such as fine crow's feet and perioral lines, Xeomin® performs comparably to Botox®.
Xeomin How does the price compare to Botox®?
In the Toronto market, the per-unit price of Xeomin® is generally comparable to Botox®. The choice should be based on: (1) which brand you have responded well to in the past; (2) whether you need"Restarting efficacy by switching brands";(3) physician familiarity; (4) Health Canada licensed indications. The decision should never be based solely on"Which is more affordable"decision.
Is Xeomin® authorized for sale by Health Canada, and is it widely available in Markham and Toronto?
Exactly what is Xeomin® made of, and how does it work to reduce wrinkles?
Does a Xeomin® injection hurt, and what is the recovery like afterward?
Can Xeomin® be combined with dermal fillers or other aesthetic treatments in the same visit?
How often should I schedule Xeomin® maintenance appointments to keep results consistent?
Real Clients · Google Reviews
What Our Clients Say
Vivian Okoth
0 reviews
Dr. Xu and the staff here are fantastic. I’ve been coming here for years and always leave satisfied! The clinic has a relaxed, comfortable, and welcoming atmosphere—I always look forward to my visits.
Mary Jane
1 reviews
I am so grateful to the friend who recommended this place to me. Dr. Xu is amazing—she is the only doctor I’ll see from now on! Everyone on the staff is incredibly friendly and helpful.
Millicent Akisa
1 reviews
She is truly outstanding! She is both friendly and professional, highly knowledgeable, and has a very warm and gentle manner. She listens carefully to your needs and takes the time to explain all the options to you.
Chen cheng
15 reviews
Vivian is extremely professional. Of all the times I've been here, her technique and service are the best. She finished my hyaluronic acid injection very quickly, with minimal pain. She's also beautiful and has a great p…
Emmaculate Matswa
1 reviews
I'm so glad I came here. Dr. Xu is incredibly knowledgeable, and every piece of advice she gave was meticulous and thoughtful. I really enjoyed talking to her about skincare. Everyone here is so warm and friendly .
Sally Yang
2 reviews
Ling was absolutely amazing! She is so friendly, kind, and welcoming. She made the whole experience so enjoyable and comfortable. Truly appreciate her warm personality and excellent service. Highly recommend!
Zara F. Bell
2 reviews
Absolutely amazing clinic. I was treated with the upmost care and respect. Felt like I've know them my whole life. The whole crew is amazing and so sweet! The service was impeccable by Dr. Dan Xu, she is literally the be…
Caroline Fan
8 reviews
I had a really pleasant visit at ID cosmetics today with Ling. I had my pico laser appointment today. Ling treated me with such kindness and care. She was really attentive prepping me for my treatment and checking in on…
Vivian Okoth
0 reviews
Dr. Xu and the staff here are fantastic. I’ve been coming here for years and always leave satisfied! The clinic has a relaxed, comfortable, and welcoming atmosphere—I always look forward to my visits.
Mary Jane
1 reviews
I am so grateful to the friend who recommended this place to me. Dr. Xu is amazing—she is the only doctor I’ll see from now on! Everyone on the staff is incredibly friendly and helpful.
Millicent Akisa
1 reviews
She is truly outstanding! She is both friendly and professional, highly knowledgeable, and has a very warm and gentle manner. She listens carefully to your needs and takes the time to explain all the options to you.
Chen cheng
15 reviews
Vivian is extremely professional. Of all the times I've been here, her technique and service are the best. She finished my hyaluronic acid injection very quickly, with minimal pain. She's also beautiful and has a great p…
Emmaculate Matswa
1 reviews
I'm so glad I came here. Dr. Xu is incredibly knowledgeable, and every piece of advice she gave was meticulous and thoughtful. I really enjoyed talking to her about skincare. Everyone here is so warm and friendly .
Sally Yang
2 reviews
Ling was absolutely amazing! She is so friendly, kind, and welcoming. She made the whole experience so enjoyable and comfortable. Truly appreciate her warm personality and excellent service. Highly recommend!
Zara F. Bell
2 reviews
Absolutely amazing clinic. I was treated with the upmost care and respect. Felt like I've know them my whole life. The whole crew is amazing and so sweet! The service was impeccable by Dr. Dan Xu, she is literally the be…
Caroline Fan
8 reviews
I had a really pleasant visit at ID cosmetics today with Ling. I had my pico laser appointment today. Ling treated me with such kindness and care. She was really attentive prepping me for my treatment and checking in on…
Grace
Local Guide · 13 reviews
I got a treatment done by Ling today and she was super friendly and helpful. She made me feel very comfortable throughout the entire process from the beginning til the end and I’d like to get it done by her again next ti…
Yvonne H
Local Guide · 54 reviews
Ling was so kind and super precise. I loved her recommendations—felt like she just knew what I needed! Thank you!
Dou Xu
2 reviews
Ling is just amazing—so gentle and professional. She really knows her stuff! I felt super cared for. The whole experience? Honestly, so relaxing.
Yan Sun
3 reviews
Dr. Dan Xu is seriously amazing—so skilled and patient! Felt super at ease the entire time. The results? Wow, just wow.
Olivia W
3 reviews
Entrusting my face to Dr. Xu and her team is reassuring, and everyone's service attitude is super nice. The clinic environment is clean and elegant, and Dr. Xu is enthusiastic and professional. I have always trusted her…
Hana Yu
9 reviews
I have been here since 3 years ago, Dr.Xu is very professional and all the staff are very nice and patient. I highly recommend this place!
xiaojie chen
7 reviews
Susie has an incredibly caring attitude, and all of her suggestions were truly helpful. I really appreciated her support!
Jackie Tse
Local Guide · 18 reviews
Dr Xu is very friendly and professional. Appointment was made quickly and the consultants provided professional and helpful advice. After the procedure, the consultant provided advice on after care and treatment plans. H…
Grace
Local Guide · 13 reviews
I got a treatment done by Ling today and she was super friendly and helpful. She made me feel very comfortable throughout the entire process from the beginning til the end and I’d like to get it done by her again next ti…
Yvonne H
Local Guide · 54 reviews
Ling was so kind and super precise. I loved her recommendations—felt like she just knew what I needed! Thank you!
Dou Xu
2 reviews
Ling is just amazing—so gentle and professional. She really knows her stuff! I felt super cared for. The whole experience? Honestly, so relaxing.
Yan Sun
3 reviews
Dr. Dan Xu is seriously amazing—so skilled and patient! Felt super at ease the entire time. The results? Wow, just wow.
Olivia W
3 reviews
Entrusting my face to Dr. Xu and her team is reassuring, and everyone's service attitude is super nice. The clinic environment is clean and elegant, and Dr. Xu is enthusiastic and professional. I have always trusted her…
Hana Yu
9 reviews
I have been here since 3 years ago, Dr.Xu is very professional and all the staff are very nice and patient. I highly recommend this place!
xiaojie chen
7 reviews
Susie has an incredibly caring attitude, and all of her suggestions were truly helpful. I really appreciated her support!
Jackie Tse
Local Guide · 18 reviews
Dr Xu is very friendly and professional. Appointment was made quickly and the consultants provided professional and helpful advice. After the procedure, the consultant provided advice on after care and treatment plans. H…
Ready to Begin Your Xeomin® Journey?
Your Free 30-Minute Consultation is conducted personally by Dr. Dan Xu, M.D., and includes a dynamic muscle assessment, review of your neurotoxin history, antibody risk discussion, and brand matching (Xeomin® / Botox® / Dysport® / Letybo®) — so we can design the most appropriate "bare-molecule" pure-formula plan for you.
Ready to improve your appearance or address your concerns with XEOMIN®? Book Now in Toronto ID Cosmetic Clinic。
Address:30 Gibson Dr, Units 113-117, Markham, ON L3R 2S3
Phone:905-477-2225
Free 30-Minute Consultation
Every consultation is conducted personally by Dr. Xu (Mon–Sat).
24 hr response · English/Chinese OK
Technology defines the possibilities. The physician defines the direction.
Identify with your own beauty.
