Letybo® in Toronto & Markham: Next-generation Korean neuromodulator
Hugel letibotulinumtoxinA · #1 market share in Korea for 9 consecutive years · Onset in 3–5 days · Results last up to 4 months · FDA 2024 & Health Canada licensed · 1:1 unit conversion with Botox®
Quick Answer
Letybo® (letibotulinumtoxinA) is a prescription neuromodulator made by Hugel in South Korea and authorized in Canada. Like other neuromodulators, it temporarily reduces muscle activity to smooth dynamic wrinkles such as frown lines, forehead creases and crow's feet. It uses a 1:1 unit conversion with Botox®, and per unit it is about 15–25% lower in price. The toxin blocks nerve signals to targeted muscles, softening contractions. At ID Cosmetic Clinic in Markham, serving Toronto and the GTA, treatments are personally performed by physician Dr. Dan Xu, M.D., CCFP. Results typically appear within days, peak around two weeks, and last three to four months per session.
View Contents (14)
Dr. Xu's Real Cases: Neuromodulators (Letybo® and others)
Real clients treated personally by Dr. Dan Xu at ID Cosmetic Clinic in Markham. Every client signed a Media Release Form. Photos are unretouched clinical records; results vary between patients with skin type and aftercare, and are not guaranteed.
01Heavy Mature Jowls Lifted
- Treatment
- neuromodulator injections, Belotero®, Chin Filler, Lip Filler Augmentation, Temple filler, Forehead Filler Augmentation, HA Filler (Juvéderm® and others), Teosyal®, Collagen Stimulator (Bellafill®, etc.), Perioral Rejuvenation and Eye Rejuvenation / Brightening Injections combined to lift the jowls and reveal the jawline; on this page the focus is lower-face sagging.
- Maintenance
- Continued sun protection and moisturising; review as scheduled to assess maintenance.
02Clear Jaw-Neck Line In Profile
- Treatment
- HA Filler (Juvéderm® and others) combined with neuromodulator injections to define the jawline in profile.
- Maintenance
- Review as scheduled and top up if needed to maintain.
03Heavy Upper Lids Relieved In Frontal View
- Treatment
- neuromodulator injections as a single treatment to relieve heavy upper lids.
- Maintenance
- Continued sun protection and moisturising; review as scheduled to assess maintenance.
04Deep Forehead Lines Shallower
- Treatment
- HArmonyCa™ (HA + Collagen Biostimulator), Collagen Stimulator (Bellafill®, etc.) and neuromodulator injections combined to soften deep forehead lines.
- Maintenance
- Continued sun protection and moisturising; review as scheduled to assess maintenance.
05Mature Corner Lines Lifted In Profile
- Treatment
- Chin Filler, HA Filler (Juvéderm® and others), Restylane®, Stylage®, Teosyal®, Teosyal® Hydrafill Skin Booster, Yvoire®, Collagen Stimulator (Bellafill®, etc.), Perioral Rejuvenation, Eye Rejuvenation / Brightening Injections, neuromodulator injections, masseter reduction with neuromodulator injections and Sofwave™ combined to lift the downturned corner lines.
- Maintenance
- Continued sun protection and moisturising; review as scheduled to assess maintenance.
06Receding Chin Brought Forward In Three-Quarter View
- Treatment
- HA Filler (Juvéderm® and others) as a single treatment to correct the receding chin.
- Maintenance
- Review as scheduled and top up if needed to maintain.
07Bulky Calf Muscles Made Slender
- Treatment
- Calf Slimming Injection (neuromodulator injections) as a single treatment to relax and reduce the calf muscles.
- Maintenance
- Review as scheduled and top up if needed to maintain.
08Mature Face Lifted And Refreshed Overall
- Treatment
- PicoSure®, Ultherapy® and neuromodulator injections combined to lift the face and improve tone and wrinkles.
- Maintenance
- Continued sun protection and moisturising; review as per the treatment schedule to maintain.
09Mature Forehead Lines Relaxed
- Treatment
- neuromodulator injections as a single treatment to relax the forehead lines.
- Maintenance
- Continued sun protection and moisturising; review as scheduled to assess maintenance.
10Chin Pushed Forward In Three-Quarter View
- Treatment
- HA Filler (Juvéderm® and others) as a single treatment to correct the receding chin.
- Maintenance
- Review as scheduled and top up if needed to maintain.
11Retrusion Corrected In Side View
- Treatment
- Chin Filler combined with HA Filler (Juvéderm® and others) to correct the receding chin.
- Maintenance
- Review as scheduled and top up if needed to maintain.
← swipe for more →
Why Choose ID Cosmetic Clinic for Letybo® in Toronto
Devices define the possibilities; physicians define the direction. As Korea’s #1 brand newly entering the North American market, Letybo® demands a higher standard of protocol familiarity and precise dose conversion from physicians. As one of Hugel Canada’s early certified training physicians, Dr. Xu is well-versed in the standard injection points used in Korean clinics and the dosing nuances specific to Asian faces.
Specialist in Asian Facial Aesthetics
Dr. Xu specializes in Asian facial anatomy and mimetic muscle dynamics, with an in-depth understanding of the standard injection points and dosing philosophy used in Korean clinics. She brings the Korean aesthetic of “natural, subtle refinement” directly into her Canadian clinical practice.
Hugel Canada training certification
Dr. Xu holds the official Hugel Canada Letybo® injection training certification — Hugel being the global manufacturer of Letybo® — with comprehensive expertise in letibotulinumtoxinA’s diffusion profile, onset curve, and Asian-specific dosing protocols.
80,000 injection treatment areas performed
With extensive experience across all major neurotoxin brands — Letybo®, Botox®, Dysport®, Xeomin®, and Nuceiva® — Dr. Xu selects the most appropriate option and designs personalized treatment plans based on your budget, onset requirements, maintenance interval preference, and long-term antibody management, with particular expertise in dose conversion between Letybo® and other neuromodulator brands.
All four major neurotoxin platforms available
Our clinic carries Letybo® / Botox / Dysport / Xeomin. Brand selection is guided by your budget, allergy history, and long-term plan; combination with other treatments is recommended when appropriate (e.g., Juvéderm® for filling static lines).
Bilingual consultation (English & Chinese)
Consultations are available in both Mandarin and English, so you can fully understand Letybo®’s Korean background, the unit-for-unit conversion logic relative to Botox®, and why Dr. Xu recommends this particular brand for your needs — especially if you are a first-time patient or require frequent maintenance treatments.
Conveniently located in Markham, serving Toronto and the GTA
Located in Markham, our clinic serves Toronto and the Chinese-Canadian community across the Greater Toronto Area (GTA), including clients from North York, Richmond Hill, Scarborough, and Vaughan. Evening and weekend appointments are available.
- FDA 2024 Approved Letybo® · Health Canada DIN registered (2020)
- Hugel Officially Certified Letybo® Training Physician in Canada
- Allergan / Juvéderm North America Official Trainer (peer physician training)
- CPSO-registered physician in Ontario (publicly verifiable)
- All neurotoxin injections are personally performed by Dr. Dan Xu (M.D.) — never delegated to a technician.
- Google 4.9★ · 283 patient reviews
What is Letybo®?
Letybo® is a product of Korea’s Hugel Pharmaceuticals — a Type A botulinum toxin (letibotulinumtoxinA) formulation launched in Korea in 2010, with #1 market share in Korea for 9 consecutive years. 2020 received 2024 Formally received Health Canada–licensed entering the North American market as the most anticipated next-generation neuromodulator of the past decade. Its core positioning is 900 kDa complexed protein structure + 1:1 unit equivalence with Botox® + competitive per-unit pricing, making it particularly appealing to budget-conscious patients, first-time clients, and those on high-frequency maintenance schedules.
Like Botox®, Letybo® is a 900 kDa complex protein botulinum toxin type A with the same mechanism of action — blocking nerve terminals’ SNAP-25 protein and inhibiting acetylcholine release to temporarily relax the targeted muscles. Its clinical performance is nearly identical to Botox®: 3-5 days to onset (approximately 1–2 days faster than Botox®), lasts 4 months · 1:1 unit equivalence conversion (far more straightforward than Dysport®’s 1:2.5 conversion).
Letybo’s true differentiator lies in cost-effectiveness and brand options: ① per-unit pricing is 15–25% lower than Botox® (consultation-based pricing/U); ② over 10 years of high-volume clinical data in Korea (9 consecutive years as the #1 market-share brand means tens of millions of doses administered annually); ③ the Korean clinic philosophy of “natural, subtle enhancement” is carried directly into our treatment protocols. Dr. Xu designates Letybo® as the preferred formulation for budget-conscious patients, first-time users, patients on high-volume annual maintenance, and those with a K-beauty preference.
Device / formulation technical specifications
- Generic nameletibotulinumtoxinA
- Molecular structure900 kDa Complex protein
- Mechanism of actionBlocks SNAP-25 protein · Inhibits acetylcholine release
- Onset time3-5 days (slightly faster onset than Botox®)
- Duration4 months
- FDA /2024 FDA · 2020· Health Canada–licensed
- ManufacturerHugel Pharmaceuticals (Korea)
Letybo comparison with other neurotoxins
| brand | Onset | Maintenance | Dosage conversion |
|---|---|---|---|
| Letybo® | 3-5 days | 4 months | 1:1 vs Botox |
| Botox® | 3-7 days | 4-6 months | Benchmark |
| Dysport® | 2-5 days | 3-5 months | 1:2.5 vs Botox |
| Xeomin® | 5-7 days | 3-4 months | 1:1 vs Botox |
Note: Letybo® is a Korean brand that entered the North American market in 2024. Its clinical profile is comparable to Botox®, but at a more accessible price point — making it the preferred choice for budget-conscious clients and those requiring frequent maintenance.
How Letybo® Works
Letybo® shares the same molecular mechanism as Botox® — blocking the SNAP-25 protein — with a very similar clinical onset curve. However, given the distinct injection philosophy of Korean clinics, Dr. Xu applies specific “Korean natural-look aesthetic” protocol adjustments in dosing and injection point placement.
Consultation & goal setting
Dr. Xu assesses your muscle activity by asking you to perform facial expressions (raising your brows, frowning, smiling, pursing your lips), evaluating dynamic muscle strength and residual static lines, and clearly establishes whether the goal is to “soften movement” or “completely stop expression” — Letybo®’s dosing philosophy favors the former.
Customized dosing (1:1 unit equivalence with Botox®)
Letybo and Botox® have a 1:1 unit equivalence conversion (previous Botox® 20U for glabellar lines → Letybo® 20U), so the conversion is straightforward. Dr. Xu determines the final dosage based on your individual muscle strength and facial symmetry; Korean clinics typically follow a slightly lower-dose philosophy — 10–15% lower than standard North American protocols, with a greater focus on natural results.
Precise multi-point superficial injection technique
A fine 30–32G needle is used to deliver multiple shallow injections along the natural muscle grain. Letybo®’s diffusion profile is similar to Botox® (moderate) — sitting between Xeomin® and Dysport®. The entire process takes 5–10 minutes, with minimal discomfort (comparable to a small insect bite).
3-5 days to onset
Letybo’s onset is approximately 1–2 days faster than Botox® — a feeling of muscle heaviness typically begins around Day 3–5, with full effect reached by Day 10–14. Do not self-administer additional doses if results seem minimal in the first week — allow the formulation sufficient time to bind to nerve terminals. Letybo®’s onset curve is best described as “fast but smooth” among the four major brands.
4 month maintenance period
A first injection typically lasts 4 months, comparable to Botox®. Long-term users should be mindful of antibody avoidance strategies — like Botox®, Letybo® carries a complexed protein structure, placing antibody risk in the low-to-moderate range. Dr. Xu recommends switching to Xeomin® at least once per year to reduce cumulative antibody exposure.
Cost-effectiveness & long-term antibody management — Dr. Xu’s three-line strategy
Letybo’s two key clinical advantages are competitive per-unit pricing and 1:1 Botox unit equivalence conversion; however, long-term use still requires planning around antibody risk. Dr. Xu addresses this through three key strategies to maximize both cost-effectiveness and safety.
Korean dosing philosophy
Dr. Xu follows the “conservative start” dosing protocol used in Hugel’s Korean clinics — approximately 10–15% lower than standard North American doses — prioritizing natural, subtle enhancement over a frozen appearance.
12-week interval guidelines
Regardless of the neurotoxin brand, Dr. Xu maintains a minimum 12-week interval between injections to prevent the immune system from forming antibodies through excessive exposure.
Annual brand rotation
Patients who maintain treatments at high frequency are advised to switch to Xeomin® (the “bare molecule” toxin) at least once per year to reduce cumulative antigen exposure, keeping Letybo® as their long-term primary choice.
Among my 80,000 treatment areas, Letybo® has seen the fastest patient growth over the past 12 months — driven partly by the excitement around its FDA 2024 approval, and partly by the fact that per-unit pricing 15–25% lower than Botox® translates to a genuine 20–30% cost saving for high-volume annual maintenance patients. My position on Korean brands has always been consistent: translating 14 years of refined Korean clinic protocols to Canada — rather than defaulting to the North American “high-dose” approach. — Dr. Dan Xu, M.D., CCFP · Hugel Certified Letybo Injector
Am I a Candidate for Letybo®?
You are welcome to do a preliminary self-assessment before your consultation, but suitability can only be confirmed by Dr. Xu through dynamic muscle assessment + prior neurotoxin history review + budget planning. Based on a comprehensive clinical assessment — particularly for budget-conscious clients, first-time patients, those drawn to the Korean aesthetic, or those requiring high-volume annual maintenance — Letybo® is often the optimal choice.
You may be a candidate for treatment if…
- First-time aesthetic treatment seekers who are budget-conscious and value-driven
- Clients who plan high-volume annual maintenance (200U+ / year) and are looking to reduce costs
- Clients who prefer the Korean aesthetic / “natural subtle enhancement” style
- Clients with dynamic wrinkles (glabellar lines / forehead lines / crow’s feet)
- First-time patients who prefer to start with a mainstream brand to gauge their response
- Clients who want faster onset (3–5 days) but wish to avoid Dysport®’s wider diffusion spread
- Clients seeking masseter slimming / square face improvement (high-unit treatment)
- Clients looking for a Botox / Xeomin rotation option during the interval period
Treatment is not recommended if any of the following apply…
- Pregnancy or breastfeeding
- Neuromuscular disorders (myasthenia gravis, Lambert-Eaton syndrome, ALS)
- Active infection or inflammation at the injection site
- Allergy to letibotulinumtoxinA or human serum albumin
- Currently taking aminoglycoside antibiotics
- Received another neuromodulator brand within the past 3 months
- Have developed antibodies to complexing proteins (Xeomin® recommended)
- Clients with unrealistic expectations or those seeking a completely frozen face (not recommended for Asian faces)
Clinical Scenario × Neuromodulator Brand — Dr. Xu’s Recommendation Guide
Dr. Xu has clear brand preferences for different clinical scenarios — Letybo® is the first choice for budget-conscious patients, first-time neuromodulator users, and those requiring high-volume annual maintenance:
| Clinical context | First choice | Secondary option | Reason |
|---|---|---|---|
| Budget-conscious / cost-effective | Letybo | Dysport | Per-unit cost 15–25% lower than Botox® |
| high-volume annual maintenance | Letybo | Xeomin | 1:1 Unit conversion + competitive per-unit pricing |
| Korean aesthetic medicine preference | Letybo | Botox | #1 market share in Korea for 9 years |
| First-time injection patients | Botox | Letybo | the most extensive clinical data |
| Rapid onset before a wedding | Dysport | Letybo | 2-5 days to onset |
| Long-term maintenance (5+ years) | Xeomin | Letybo | Lowest antibody risk |
| Masseter slimming (high-unit treatment) | Letybo / Botox | Dysport | 1:1 unit conversion + competitive per-unit pricing |
Letybo® Treatment Planning
Letybo neurotoxin treatment is a physician-tailored procedure. Dr. Xu designs a 4-month cyclic maintenance plan. For patients requiring high-volume annual maintenance, it is recommended to maintain regular intervals of 12 weeks or more, minimizing the risk of antibody formation, with a mid-year switch to Xeomin® recommended to reduce cumulative antigen exposure.
Initial consultation and goal assessment
A free 30-minute consultation includes dynamic expression assessment, review of prior neurotoxin history, allergy screening, and an explanation of the “Korean natural look” philosophy.
Customized dosing (1:1 Botox® conversion)
Dr. Xu converts your previous Botox® dosage to Letybo® on a 1:1 unit basis (glabellar lines 20U / crow’s feet bilateral 16–24U / forehead lines 12–16U), starting conservatively on the first treatment.
D14 Follow-up refinement
D14 is the assessment window for Letybo®’s full effect. Dr. Xu evaluates symmetry and coverage, and if needed, performs a 5–10 U touch-up (complimentary for first-time treatments).
4-month maintenance cycle
We recommend scheduling your maintenance injection when results have diminished by approximately 70% — rather than waiting for full wear-off. For patients receiving high-volume treatments annually, substituting one session with Xeomin® is advised to minimize antibody risk.
Typical treatment cycle timeline
Below is the standard timeline for Letybo® clients, from initial consultation through the maintenance period:
| Treatment timeline | Contents |
|---|---|
| Day 0 | Free 30-Minute Consultation (dynamic muscle assessment + neuromodulator treatment history + budget and goals discussion) |
| Day 0 (injection day) | Injection may be performed immediately following consultation · Entire procedure takes 5–10 minutes |
| D3-D5 | Initial effect visible · Muscles begin to feel heavier |
| D10-D14 | Full effect reached · Dynamic wrinkles visibly reduced |
| D14 Follow-up | Symmetry and coverage assessment · Touch-up of 5–10U if needed (complimentary at first visit) |
| Month 4 | Results diminished by 50–70% · Entering the maintenance injection window |
| 3 times per year | Minimum 12-week intervals maintained consistently · One mid-cycle switch to Xeomin® recommended for rotation |
Exact units and treatment intervals are customized by Dr. Xu at consultation, based on your muscle strength, treatment area, and budget.
Indications treatable with Letybo®
Letybo® delivers consistent results for dynamic wrinkles, masseter reduction, and high-unit treatment areas. For the concerns most common in Asian faces — glabellar lines, crow’s feet, forehead lines, masseter hypertrophy, and facial contouring — Dr. Xu has developed dosing protocols equivalent to Botox® (1:1 unit conversion).
Glabellar lines (“11” lines)
For dynamic contraction of the corrugator supercilii and depressor supercilii muscles, Letybo® at 20 U is the FDA- andDynamic wrinkles Over 80% improvement, using the standard 5-point injection technique.
20U / Every 4 monthsForehead lines
For dynamic horizontal forehead lines caused by frontalis muscle contraction, Letybo® at 12–20 U performs exceptionally well on mid-sized foreheads. Its moderate diffusion profile is ideal for Korean-style subtle refinement that preserves a natural degree of brow elevation.
12-20U / Every 4 monthsCrow’s feet
For dynamic contraction of the lateral orbicularis oculi, Letybo® at 8–12 U per side allows precise diffusion control, preserving the natural smile lines at the outer corners of the eyes — the hallmark of the Korean aesthetic: natural, understated results.
Bilateral 16–24U / every 4 monthsMasseter slimming (square face)
This is one of the most requested treatments among Asian women. For masseter hypertrophy, bilateral injections of 30–50 U Letybo® per side effectively reduce muscle volume, and the 1:1 Botox unit conversion + competitive per-unit pricing make high-unit masseter treatments more cost-effective.
Bilateral 60–100U / every 4–6 monthsBrow Lift
Selectively relaxing the brow depressor muscles produces a subtle lift in brow position. Letybo® is administered at a precise micro-dose of 4–10U to avoid an overly arched, “surprised” appearance — the Korean aesthetic philosophy favors a gentle brow lift rather than a dramatic elevation.
4-10U / Every 4 monthsTrapezius slimming (shoulder contouring)
For trapezius hypertrophy causing a bulky shoulder-neck profile, Letybo® at 50–100 U per side can create a slimmer, more elongated “swan neck” contour — one of the signature treatments in the Korean aesthetic philosophy.
Bilateral 100–200 U / every 4–6 monthsGummy smile
Overactive levator labii superioris alaeque nasi (LLSAN) causes excessive gum exposure when smiling. Letybo® precisely targets the LLSAN muscle at 2–4 U per side, producing a natural smile curve with diffusion control comparable to Botox®.
4-8U / Every 4 monthsNeck rejuvenation (Nefertiti Lift)
Platysmal banding: Letybo® administered along the bands at 40–60 U can soften the cords and provide a mild lift to the jawline. The combination of high-unit requirements and competitive per-unit pricing makes Letybo® particularly well suited for this indication.
40-80U / Every 4 months8 Core Indications × Letybo® Dosage × Treatment Cycle Reference Table
| Indications | Letybo Dosage | ≈ Botox Units | maintenance interval |
|---|---|---|---|
| Glabellar lines | 20U (FDA / | 20U | 4 months |
| Forehead lines | 12-20U | 12-20U | 4 months |
| Crow’s feet | 16–24 U per side (bilateral) | 16–24 U per side (bilateral) | 4 months |
| brow lift | 4-10U | 4-10U | 4 months |
| Masseter slimming | 60–100 U per side (bilateral) | 60–100 U per side (bilateral) | 4-6 months |
| Trapezius slimming (shoulder contouring) | Bilateral 100–200U | Bilateral 100–200U | 4-6 months |
| Gummy smile | 4-8U | 4-8U | 3-4 months |
| Neck lines — Nefertiti Lift | 40-80U | 40-80U | 4 months |
Pre-Procedure Instructions · Injection Process · Post-Procedure Care
There is minimal downtime following a Letybo® injection; however, post-procedure care within the first 4 hours can affect the final symmetry and longevity of results. Dr. Xu will walk you through each aftercare instruction immediately after treatment.
Pre-procedure preparation
- Avoid aspirin, ibuprofen, and Omega-3 supplements for 1 week prior to injection (to minimize bruising). Do not stop a prescribed medication without your prescriber’s advice.
- Avoid alcohol (24 hours before injection)
- Disclose all current medications (including antibiotics and antihypertensives)
- Arrive without makeup on the injection area. Eating normally beforehand is fine.
- Please provide your full neurotoxin history prior to consultation, including brand, dosage, and any changes in onset or duration over time.
- Please inform us of any allergy to human serum albumin (Letybo® contains human serum albumin as an excipient)
During the injection procedure
- Facial cleansing + injection site mapping (3–5 minutes)
- Fine 30–32G needle used for multi-point shallow injections
- A mild, brief stinging sensation similar to a small insect bite
- Single session duration: 5–10 minutes (depending on number of areas treated)
- Immediately after injection, minor pinpoint redness or small bumps may appear at the injection sites (resolving within 30 minutes).
Post-procedure care
- Remain upright for at least 4 hours after injection (do not lie flat, to prevent diffusion)
- Avoid massaging, rubbing or pressing the injection area for 24 hours post-treatment unless Dr. Xu instructs you otherwise
- Avoid hot yoga, sauna, and strenuous exercise within 24 hours of treatment.
- Avoid alcohol for 24 hours after treatment (alcohol increases bruising risk)
- Resume work and social activities immediately after injection (minimal downtime)
- Attend the D14 follow-up to assess symmetry and coverage (first touch-up is complimentary)
- Keep using your usual SPF 50+ sunscreen. Tell us if you plan to fly soon after treatment.
D0-D30 Full onset timeline
| Timeline | What clients should do — and what to avoid |
|---|---|
| D0 (on the day of injection) | Stay upright for at least 4 hours · No massage · No lying flat · Ask us before applying makeup over minor pinpoint redness |
| D1-D2 | Possible mild sensation of heaviness in the head · Occasional bruising · Normal daily activities can be resumed |
| D3-D5 (initial effect visible) | Muscles begin to feel heavier · Dynamic wrinkles start to soften · No extra injections are needed before full results appear; any touch-up is assessed at your follow-up |
| D10-D14 (full effect achieved) | Dynamic lines visibly reduced · Often noticeable in photo comparisons |
| D14 (follow-up window) | Symmetry assessment · Small touch-up if needed (complimentary at first visit) |
| D30+ | Stable phase · Maintenance commonly every 3–4 months |
Advantages of Letybo®
Technology defines what is possible. The physician defines the direction — the key advantage of Letybo® is #1 market share in Korea + 1:1 Botox® unit conversion + competitive per-unit pricing + Korean natural-look philosophy, giving physicians a more accessible option for budget-conscious patients, first-time users, and those requiring high-volume annual maintenance.
#1 market share in Korea for 9 consecutive years
Hugel’s real-world clinical refinement in the world’s largest market for Asian faces.
FDA 2024 Regulatory approval
The latest-generation neuromodulator in North America · Dual regulatory approval.
1:1 Botox Unit equivalence conversion
Dosing is straightforward — existing Botox® unit dosages can be transferred directly.
Accessible per-unit pricing (consultation-based pricing per unit)
15–25% lower cost than Botox® · Especially cost-effective for high-unit treatments.
3-5 days for stable onset
Slightly faster onset than Botox® · 2–3 days faster than Xeomin®.
4 month maintenance period
Comparable to Botox® · Well-suited for a regular 12-week interval protocol.
Korean natural-look philosophy
“Conservative start” dosing protocol · preserving natural expression and movement.
well-suited for high-unit treatment needs
Masseter / trapezius / neck lines · Per-unit cost advantage amplifies savings.
Letybo vs Botox vs Dysport vs Xeomin: comparison of four neuromodulator brands
| brand | Onset time | maintenance period | Dosage conversion | Per-unit price (CAD/U) |
|---|---|---|---|---|
| Letybo® | 3-5 days | 4 months | 1:1 vs Botox | Consultation-based pricing |
| Botox® | 3-7 days | 4-6 months | Benchmark | Consultation-based pricing |
| Dysport® | 2-5 days | 3-5 months | 1:2.5 vs Botox | Consultation-based pricing (×2.5) |
| Xeomin® | 5-7 days | 3-4 months | 1:1 vs Botox | Consultation-based pricing |
Note: Letybo® is Korea’s #1 neuromodulator brand, newly available in North America as of 2024, with the most competitive per-unit price, particularly well-suited for budget-conscious clients and those requiring high-unit annual maintenance. For a detailed brand comparison, please refer to the Neuromodulator Brand Selection Guide.
Dr. Dan Xu, M.D., CCFP
ID Cosmetic Clinic Founder & Medical Director · Author of Timeless Asian Beauty · Hugel Certified Letybo Injector
As a widely respected Chinese-Canadian medical aesthetic physician in Toronto, Dr. Dan Xu is recognized for her deep clinical expertise, a refined sense of aesthetic artistry, and a keen cultural understanding. With over 80,000 procedures, she brings injectable and laser clinical expertise, including refined use of all major neurotoxin brands: Letybo®, Botox®, Dysport®, and Xeomin®.
Dr. Xu holds Hugel Canada Letybo® Training Certification (Hugel is the global manufacturer of Letybo®) and has developed a thorough command of letibotulinumtoxinA’s onset curve, dosing protocols for Asian faces, and clinical switching strategies between neuromodulator brands. She introduced Letybo® to the clinic in parallel with its Health Canada–licensed status in 2024 and has since completed Letybo® prescription transitions for hundreds of budget-conscious and high-frequency maintenance patients.
Her aesthetic philosophy is both concise and profound: “Beauty should bring out the best in you — not change who you are.” This means embracing the Korean clinic philosophy of “natural subtle refinement” when injecting Letybo® — preserving natural facial expression and movement in Asian faces.
Professional Certifications & Credentials
- Education — M.D. + Family Medicine Specialty Certification (CCFP)
- Authority — Hugel Certified Letybo® Training Physician in Canada
- Authority — Allergan / Juvéderm North America Official Trainer
- Authority — Merz Canada Xeomin® Training Certification
- Authority — Galderma Canada Dysport® Training Certification
- Authority — Candela Medical Canada Key Opinion Leader
- Authority — Cynosure PicoSure Pro Canada KOL
- Authority — Sofwave Key Opinion Leader
- Authority — McMaster University Clinical Preceptor (Clinical training physician)
- Authority — IMCAS International Medical Aesthetics Conference Speaker
- Trust — CPSO Registered physician · Publicly verifiable
- Trust — Author of Timeless Asian Beauty (2024)
《Timeless Asian Beauty》
Timeless Asian Beauty, written by Dr. Dan Xu, is a book dedicated toAsian facesa landmark aesthetic guide tailored to its readers. Rather than prescribing rigid beauty standards, the book invites readers to explore beauty through the lens of culture, anatomy, and self-awareness —Redefining beauty. In the book, regardingKorean natural-look neuromodulator philosophy and multi-brand rotation strategy, It forms the clinical blueprint for Letybo® prescribing at ID Cosmetic Clinic.
Drawing on cross-border clinical experience in China, Korea, and Canada, Dr. Xu challenges the long-dominant Western-centric aesthetic bias in his book, for the first time addressingthe bone structure, mimetic muscle orientation, and aging trajectory of Asian faces, a systematic long-term neuromodulator maintenance framework — a comprehensive strategy covering brand rotation, dose titration, and budget optimization.
At the heart of the book lies the essence of Asian aesthetics —natural, soft, and expressive. Dr. Xu emphasizes in the book: a well-executed neuromodulator treatment should never result in a frozen face — rather, it isSoftening dynamic wrinkles while preserving natural facial expression — This aligns perfectly with Letybo®’s philosophy of Korean-style subtle, natural-looking refinement.
Identify with your own beauty.
Identify with your own beauty. — Dr. Dan Xu, M.D.
Why Trust Letybo® at ID Cosmetic Clinic?
Real injection experience
- 10+ years of dedicated clinical practice in neurotoxin injections
- 80,000 cumulative injection procedures performed
- Among the first clinics to introduce Letybo® following its FDA 2024 approval
- Hundreds of budget-conscious and high-frequency maintenance patients successfully transitioned to Letybo®
- Comprehensive Before & After photo documentation for every patient
Medical professional training
- M.D. Comprehensive medical school training
- CCFP Family Medicine Specialty Certification
- Expert knowledge of facial anatomy and neuromuscular mechanisms
- Deep understanding of dual-track Korean and North American dosing protocols
- Expertise in cross-brand neurotoxin unit conversion (4 brands)
Industry-recognized credentials
- Hugel Certified Letybo® Training Physician in Canada
- Allergan / Juvéderm North America Official Trainer
- Merz Canada Xeomin® Training Certification
- Galderma Canada Dysport® Training Certification
- Candela Medical Canada Key Opinion Leader
- Cynosure PicoSure Pro Canada KOL
- Sofwave Key Opinion Leader
- McMaster University Clinical Teaching Physician
- IMCAS International conference speaker
Transparent and verifiable
- CPSO Registered practicing physician (publicly verifiable)
- Google 4.9★ · 283 patient reviews
- Written informed consent form signed and unit dosage recorded at every injection session
- All Before & After images are unretouched.
- Author of Timeless Asian Beauty (2024)
Letybo® is not a “cheap alternative to Botox®” — rather, a combination of Korea’s #1 brand + 1:1 unit equivalence + genuine value
Like Botox®, Letybo® is a 900 kDa complex-protein botulinum toxin type A with an identical mechanism of action — but with nine consecutive years as the #1 market-share holder in Korea and the real-world clinical refinement that comes with it, plus 1:1 Botox unit-for-unit conversion + 15–25% lower cost per unit than Botox®, making it a clinically compelling option for budget-conscious clients, first-time patients, and those requiring high-volume annual maintenance.
As a Hugel Canada certified injection physician, Dr. Xu will tailor the treatment through personalized decision-making based on your budget, injection history, onset expectations, and long-term goals. Letybo®’s true value is not about “replacing another brand” — it is about making your long-term neurotoxin maintenance plan more sustainable without compromising quality.
Letybo® Pricing: How It Compares with Botox®
Pricing is based on units (U). Per unit, Letybo® is the most cost-effective among the four major brands — approximately 15–25% lower than Botox®. Following a Free 30-Minute Consultation, Dr. Xu will customize your unit dosage and provide a personalized quote. Note: Letybo® and Botox® share a 1:1 unit conversion — your existing Botox® dosage can be transferred directly. Savings are especially significant for high-unit treatments (masseter / trapezius).
Priced per unit · Glabellar lines 20 U / Forehead lines 12–20 U / Crow’s feet (bilateral) 16–24 U
Masseter / trapezius / neck lines / annual maintenance packages · Exclusive pricing for high-unit treatments
- We accept VISA / Mastercard / Amex / Debit / E-transfer
- Affirm / PayBright financing available (select treatment packages)
- Private insurance: some commercial extended health benefit (EHB) plans may reimburse consultation fees — inquire about your individual case
- OHIP: cosmetic treatments are not covered by insurance
- All new clients receive a 30-minute complimentary consultation & assessment
Common Risks · Contraindications · Safety Protocol
Transparency in medical aesthetics is itself a marker of trustworthiness. We openly share all possible reactions, serious risks, contraindications, and absolute exclusions so you are fully informed before your consultation. Before every injection, Dr. Xu reviews Letybo®’s risk profile and long-term planning strategy with you, point by point.
Common reactions (may occur shortly after injection)
- Mild redness, swelling, or small bumps at injection points (30 minutes to 2 hours to resolve)
- bruising (5-7 days to resolve naturally; Arnica may be used to speed recovery)
- Feeling of tightness or heaviness in the head (D1-D5 common; gradually resolves with time)
- Mild headache (24-48 hours; acetaminophen may be taken for relief)
- Mild soreness or pressure at the injection site (Mild chewing weakness in the 1–2 weeks following masseter injection is normal)
Serious risks (rare, but must be disclosed)
- Eyelid ptosis (upper eyelid droop) — Most commonly seen when glabellar injections diffuse to the levator palpebrae superioris; Dr. Xu reduces this risk to <1% through precise injection point spacing. If it occurs, it typically resolves on its own within 4–6 weeks; Apraclonidine eye drops can be used to speed recovery.
- Lateral brow ptosis / facial expression asymmetry — Letybo has moderate diffusion; this is occasionally noted in Asian women with thinner mimetic muscles. A day-14 follow-up allows a 5–10 U touch-up to refine symmetry if needed.
- Unnatural smile — Diffusion into the zygomaticus major during crow’s feet injection; Dr. Xu avoids this by maintaining a distance of 1.5 cm or more from the lateral canthus.
- allergic reaction — Extremely rare (Letybo® excipients contain human serum albumin); patients with known allergies must disclose prior to treatment.
- Antibody formation (treatment failure) — Letybo antibody risk: low to moderate. For high-frequency annual users, incorporating one Xeomin® session mid-cycle is recommended to reduce cumulative antigen exposure.
- Infection at the injection site — Extremely rare; preventable with proper sterile technique
Absolute contraindications (do not treat)
- Pregnancy / breastfeeding
- Neuromuscular disorders (myasthenia gravis, Lambert-Eaton syndrome, ALS, multiple sclerosis)
- Active infection or inflammation at the injection site
- Severe allergy to letibotulinumtoxinA or human serum albumin
- Currently taking aminoglycoside antibiotics (e.g., gentamicin, which potentiates toxin activity)
- Injection of another neurotoxin brand within the past 3 months (to avoid compounding antibody exposure)
- Unrealistic expectations (e.g., requesting a completely frozen face or absolute symmetry)
- Active depression, anxiety, or emotional instability (we recommend stabilizing your mental health before proceeding)
Safety protocols strictly enforced by Dr. Xu
- Every patient undergoes a dynamic muscle assessment, review of prior neurotoxin history, and long-term treatment planning discussion before each injection.
- Written informed consent form signed before every injection, with detailed unit records kept on file.
- All injections are spaced a minimum of 12 weeks apart (to reduce antibody formation)
- All Letybo® injections are performed personally by Dr. Dan Xu, M.D. — never delegated to a technician
- Mandatory D14 follow-up to assess symmetry · Complimentary touch-up at first visit
- Cumulative unit documentation maintained · Ongoing tracking of onset and fading signals
- Letybo product sourced through Hugel’s Canadian domestic cold chain · Maintained at 2–8°C throughout
Frequently Asked Questions About Letybo® in Toronto
Answered personally by Dr. Dan Xu — based on the most frequently asked questions from patients in Toronto and Markham.How Is Neurotoxin Treatment Priced? Why Do Costs Vary So Much Between Clinics?
The difference in pricing does not come from the device or product itself — it comes from the depth of assessment. The appropriate dosage, injection points, combination strategy, and whether a multi-modality plan is needed for neuromodulator treatment can only be determined through a physician consultation — this cannot be assessed from a standard price list alone.
Routine, straightforward cases can be carried out by our trained medical team following Dr. Xu's protocols, making them more accessible. Complex cases, those with special contraindications, or revision cases require Dr. Xu's direct involvement throughout — and pricing reflects that level of medical resource. For all injectable treatments, we insist on physician-performed injections. For laser and energy-based treatments, the price difference comes down to the clinical experience gap between physician-performed and technician-performed procedures (physician vs. technician). Treatment plans and costs are determined by your clinical needs — not by a price list. First-visit clients receive a complimentary 30-minute consultation and assessment, at which Dr. Xu will discuss specifics with you based on the evaluation findings.
Which country is Letybo® from, and why is it called "Korea's No. 1"?
Is Letybo® better than Botox®? How do they differ?
How do I choose between Letybo®, Xeomin® and Dysport®?
How soon does Letybo® work, and how long does it last?
Is Letybo® suitable for first-time neuromodulator patients?
Can Letybo® cause post-inflammatory hyperpigmentation (PIH)?
When can I wear makeup, exercise or fly after Letybo®?
Is Letybo® authorized for sale by Health Canada, and is it widely available in Canada?
Can neuromodulator treatments like Letybo® be combined with dermal fillers or skin-resurfacing procedures?
Can I switch from Botox® to Letybo®?
Real Clients · Google Reviews
What Our Clients Say
Vivian Okoth
0 reviews
Dr. Xu and the staff here are fantastic. I’ve been coming here for years and always leave satisfied! The clinic has a relaxed, comfortable, and welcoming atmosphere—I always look forward to my visits.
Mary Jane
1 reviews
I am so grateful to the friend who recommended this place to me. Dr. Xu is amazing—she is the only doctor I’ll see from now on! Everyone on the staff is incredibly friendly and helpful.
Millicent Akisa
1 reviews
She is truly outstanding! She is both friendly and professional, highly knowledgeable, and has a very warm and gentle manner. She listens carefully to your needs and takes the time to explain all the options to you.
Chen cheng
15 reviews
Vivian is extremely professional. Of all the times I've been here, her technique and service are the best. She finished my hyaluronic acid injection very quickly, with minimal pain. She's also beautiful and has a great p…
Emmaculate Matswa
1 reviews
I'm so glad I came here. Dr. Xu is incredibly knowledgeable, and every piece of advice she gave was meticulous and thoughtful. I really enjoyed talking to her about skincare. Everyone here is so warm and friendly .
Sally Yang
2 reviews
Ling was absolutely amazing! She is so friendly, kind, and welcoming. She made the whole experience so enjoyable and comfortable. Truly appreciate her warm personality and excellent service. Highly recommend!
Zara F. Bell
2 reviews
Absolutely amazing clinic. I was treated with the upmost care and respect. Felt like I've know them my whole life. The whole crew is amazing and so sweet! The service was impeccable by Dr. Dan Xu, she is literally the be…
Caroline Fan
8 reviews
I had a really pleasant visit at ID cosmetics today with Ling. I had my pico laser appointment today. Ling treated me with such kindness and care. She was really attentive prepping me for my treatment and checking in on…
Vivian Okoth
0 reviews
Dr. Xu and the staff here are fantastic. I’ve been coming here for years and always leave satisfied! The clinic has a relaxed, comfortable, and welcoming atmosphere—I always look forward to my visits.
Mary Jane
1 reviews
I am so grateful to the friend who recommended this place to me. Dr. Xu is amazing—she is the only doctor I’ll see from now on! Everyone on the staff is incredibly friendly and helpful.
Millicent Akisa
1 reviews
She is truly outstanding! She is both friendly and professional, highly knowledgeable, and has a very warm and gentle manner. She listens carefully to your needs and takes the time to explain all the options to you.
Chen cheng
15 reviews
Vivian is extremely professional. Of all the times I've been here, her technique and service are the best. She finished my hyaluronic acid injection very quickly, with minimal pain. She's also beautiful and has a great p…
Emmaculate Matswa
1 reviews
I'm so glad I came here. Dr. Xu is incredibly knowledgeable, and every piece of advice she gave was meticulous and thoughtful. I really enjoyed talking to her about skincare. Everyone here is so warm and friendly .
Sally Yang
2 reviews
Ling was absolutely amazing! She is so friendly, kind, and welcoming. She made the whole experience so enjoyable and comfortable. Truly appreciate her warm personality and excellent service. Highly recommend!
Zara F. Bell
2 reviews
Absolutely amazing clinic. I was treated with the upmost care and respect. Felt like I've know them my whole life. The whole crew is amazing and so sweet! The service was impeccable by Dr. Dan Xu, she is literally the be…
Caroline Fan
8 reviews
I had a really pleasant visit at ID cosmetics today with Ling. I had my pico laser appointment today. Ling treated me with such kindness and care. She was really attentive prepping me for my treatment and checking in on…
Grace
Local Guide · 13 reviews
I got a treatment done by Ling today and she was super friendly and helpful. She made me feel very comfortable throughout the entire process from the beginning til the end and I’d like to get it done by her again next ti…
Yvonne H
Local Guide · 54 reviews
Ling was so kind and super precise. I loved her recommendations—felt like she just knew what I needed! Thank you!
Dou Xu
2 reviews
Ling is just amazing—so gentle and professional. She really knows her stuff! I felt super cared for. The whole experience? Honestly, so relaxing.
Yan Sun
3 reviews
Dr. Dan Xu is seriously amazing—so skilled and patient! Felt super at ease the entire time. The results? Wow, just wow.
Olivia W
3 reviews
Entrusting my face to Dr. Xu and her team is reassuring, and everyone's service attitude is super nice. The clinic environment is clean and elegant, and Dr. Xu is enthusiastic and professional. I have always trusted her…
Hana Yu
9 reviews
I have been here since 3 years ago, Dr.Xu is very professional and all the staff are very nice and patient. I highly recommend this place!
xiaojie chen
7 reviews
Susie has an incredibly caring attitude, and all of her suggestions were truly helpful. I really appreciated her support!
Jackie Tse
Local Guide · 18 reviews
Dr Xu is very friendly and professional. Appointment was made quickly and the consultants provided professional and helpful advice. After the procedure, the consultant provided advice on after care and treatment plans. H…
Grace
Local Guide · 13 reviews
I got a treatment done by Ling today and she was super friendly and helpful. She made me feel very comfortable throughout the entire process from the beginning til the end and I’d like to get it done by her again next ti…
Yvonne H
Local Guide · 54 reviews
Ling was so kind and super precise. I loved her recommendations—felt like she just knew what I needed! Thank you!
Dou Xu
2 reviews
Ling is just amazing—so gentle and professional. She really knows her stuff! I felt super cared for. The whole experience? Honestly, so relaxing.
Yan Sun
3 reviews
Dr. Dan Xu is seriously amazing—so skilled and patient! Felt super at ease the entire time. The results? Wow, just wow.
Olivia W
3 reviews
Entrusting my face to Dr. Xu and her team is reassuring, and everyone's service attitude is super nice. The clinic environment is clean and elegant, and Dr. Xu is enthusiastic and professional. I have always trusted her…
Hana Yu
9 reviews
I have been here since 3 years ago, Dr.Xu is very professional and all the staff are very nice and patient. I highly recommend this place!
xiaojie chen
7 reviews
Susie has an incredibly caring attitude, and all of her suggestions were truly helpful. I really appreciated her support!
Jackie Tse
Local Guide · 18 reviews
Dr Xu is very friendly and professional. Appointment was made quickly and the consultants provided professional and helpful advice. After the procedure, the consultant provided advice on after care and treatment plans. H…
Medically reviewed by Dr. Dan Xu, M.D., CCFP · Founder & Medical Director, ID Cosmetic Clinic
The clinical content on this page is reviewed by Dr. Xu.
Ready to begin your Letybo® journey?
Your free 30-minute consultation is conducted personally by Dr. Dan Xu, M.D. It includes a dynamic muscle assessment, a review of your neuromodulator history, a long-term treatment planning discussion, and brand matching (Letybo® / Botox® / Dysport® / Xeomin®) — all to design the most cost-effective, naturally refined plan for you.
Ready to say goodbye to wrinkles with Letybo®? Book Now at our Toronto ID Cosmetic Clinic, Experience professional care and outstanding results.
Address:30 Gibson Dr, Units 113-117, Markham, ON L3R 2S3
Phone:905-477-2225
Free 30-Minute Consultation
Every consultation is conducted personally by Dr. Xu (Mon–Sat).
24 hr response · English/Chinese OK
Technology defines what is possible. The physician defines the direction.
Identify with your own beauty.
